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Publications: General

Manuscripts

  Optimizing Combination Chemotherapy by Controlling Drug Ratios | Mayer & Janoff, Mol Interv 2007 Aug; 7(4): 216-223
   
  Ratiometric dosing of anticancer drug combinations: Controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice | Mayer et al, Mol Cancer Ther 2006 Jul; 5(7): 1854-1863

Abstracts
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  Ratiometric Dosing of Anticancer Drug Combinations | Janoff et al, AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics: Discovery, Biology and Clinical Applications 2006
 

 

 


CombiPlex® technology is a novel approach that identifies molar ratios of drugs that will deliver a synergistic benefit and locks the desired ratio in a nano-scale drug delivery vehicle that delivers and maintains the ratio in patients with the goal of improving clinical outcomes.

 

 

 

 

 

  
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